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Ultra-High-Field Sodium Imaging of the Human Brain at 9.4 Tesla

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons84405

Fiege D, Felder J, Celik A, Mirkes,  C
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Romanzetti, S., Fiege D, Felder J, Celik A, Mirkes, C., & Shah, N. (2012). Ultra-High-Field Sodium Imaging of the Human Brain at 9.4 Tesla. Poster presented at 20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-B7C0-F
Abstract
Monitoring the strongly regulated sodium content in vivo is of great interest for a variety of diseases. Imaging this nucleus is difficult due to its low concentration and fast relaxation. Using an ultra-high field scanner at 9.4 Tesla, a dedicated RF coils and the efficient Twisted Projection Imaging sequence, 2mm nominal isotropic sodium images of the human brain were acquired. Comparison with an MP-RAGE image shows the fine anatomical details, while a 4T comparison shows the great SNR improvement.