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Poster

Scyllo-Inositol detection in the human spinal cord

MPG-Autoren
http://pubman.mpdl.mpg.de/cone/persons/resource/persons84402

Henning,  A
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Zitation

Hock, A., Fuchs A, MacMillan EL, Kreis R, Kollias Ss, Boesiger, P., & Henning, A. (2012). Scyllo-Inositol detection in the human spinal cord. Poster presented at 20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia.


Zitierlink: http://hdl.handle.net/11858/00-001M-0000-0013-B7BA-E
Zusammenfassung
Scyllo-Inositol (sI) is one of the stereoisomers of inositol yielding to a singlet resonance at a chemical shift of 3.35 ppm in 1H MR spectroscopy (MRS). This work represents the first report of sI detection in the human spinal cord, which was enabled by non-water suppressed metabolite cycled 1H MRS at 3T. The results show an increased mI/Creatine and sI/Creatine ratio compared to the brain which might be an indicator of a different metabolism in the spinal cord.