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Distortion-free high-resolution fMRI at 9.4 T

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons83898

Ehses,  P
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons83838

Budde,  J
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84213

Shajan,  G
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons84187

Scheffler,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Ehses, P., Budde, J., Shajan, G., & Scheffler, K. (2012). Distortion-free high-resolution fMRI at 9.4 T. Poster presented at 20th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-B798-9
Abstract
SNR benefits allow for significantly higher resolution in BOLD fMRI at ultra-high fields. On the flip side, faster T2* relaxation leads to blurring and increased B0 field inhomogeneities aggravate distortion artifacts in EPI BOLD imaging at higher fields. In this work, a single-echo gradient-echo sequence is presented, that is optimized for high BOLD SNR by combining the concept of echo-shifting with an interleaved slice order. The method is demonstrated in finger tapping experiments on a human 9.4T system. The result is a BOLD activation map with 1mm isotropic resolution virtually free from distortions.