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High-resolution Fourier-encoded sub-millisecond echo time musculoskeletal imaging at 3 Tesla and 7 Tesla


Bär P, Scheffler,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Deligianni, X., Bär P, Scheffler, K., Trattnig, S., & Bieri, O. (2012). High-resolution Fourier-encoded sub-millisecond echo time musculoskeletal imaging at 3 Tesla and 7 Tesla. Magnetic Resonance in Medicine, Epub ahead. doi:10.1002/mrm.24578.

Purpose: The feasibility of imaging musculoskeletal fibrous tissue components, such as menisci, ligaments, and tendons, with a conventional spoiled gradient echo technique is explored in vivo at 3 T and 7 T. Methods: To this end, the echo time (TE1) of a conventional Fourier-encoded multicontrast three-dimensional SGPR sequence is minimized by using nonselective excitation pulses, highly asymmetric readouts, and a variable TE1 along the phase and slice encoding direction. In addition, a fully sampled second echo image (with TE2 >> TE1) can be used to highlight components with short transverse relaxation times in a difference image with positive contrast. Results: Fourier-encoded spoiled gradient echo sequences are able to provide sub-millisecond TE1 of about 800 μs for typical in-plane resolutions of about 0.5 x 0.5 mm2. As a result, high-resolution positive contrast images of fibrous tissues can be generated within clinically feasible scan-time of about 2–7 minutes. Conclusion: After optimization, Fourier-encoded spoiled gradient echo provides a highly robust and flexible imaging technique for high-resolution positive contrast imaging of fibrous tissue that can readily be used in the clinical routine.