Hilfe Wegweiser Datenschutzhinweis Impressum Kontakt





Effect of the homogeneity of the column set on the performance of a simulated moving bed unit. Part I: Theory


Seidel-Morgenstern,  A.
Physical and Chemical Foundations of Process Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society;
Otto-von-Guericke-Universität Magdeburg, External Organizations;

Externe Ressourcen
Es sind keine Externen Ressourcen verfügbar
Volltexte (frei zugänglich)
Es sind keine frei zugänglichen Volltexte verfügbar
Ergänzendes Material (frei zugänglich)
Es sind keine frei zugänglichen Ergänzenden Materialien verfügbar

Mihlbachler, K., Fricke, J., Yun, T., Seidel-Morgenstern, A., Schmidt-Traub, H., & Guiochon, G. (2001). Effect of the homogeneity of the column set on the performance of a simulated moving bed unit. Part I: Theory. Journal of Chromatography A, 908(1-2), 49-70. doi:10.1016/S0021-9673(00)00935-3.

Although it is impossible to manufacture identical columns for use in a simulated moving bed (SMB) process, theoretical studies assume that all the columns in a SMB unit have identical characteristics. In practice, calculations in modeling and optimization studies are made with the average values of each column parameter set. In this report, the effects on SMB process performance caused by column-to-column fluctuations of the parameters are discussed. As a first step, we show how the differences in porosity of the columns may be taken into account with a revised set of separation conditions. Reductions in the purity of the extract and the raffinate streams are quantitatively related to the column-to-column fluctuations of the retention times of the two components arising from these porosity differences. For the sake of simplicity, the discussion first addresses the case of a four-column SMB operating under linear conditions. Then, the scope is extended to the cases of SMB units incorporating several columns in each section and to SMB units operating under nonlinear conditions. © 2001 Elsevier Science B.V. [accessed 2013 November 29th]