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Parametric study of coupling chromatography and crystallization for efficient enantioseparations

MPS-Authors
http://pubman.mpdl.mpg.de/cone/persons/resource/persons86301

Gedicke,  K.
Physical and Chemical Foundations of Process Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons86349

Kaspereit,  M.
Physical and Chemical Foundations of Process Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons86477

Seidel-Morgenstern,  A.
Physical and Chemical Foundations of Process Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society;
Otto-von-Guericke-Universität Magdeburg, External Organizations;

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Citation

Gedicke, K., Kaspereit, M., & Seidel-Morgenstern, A. (2003). Parametric study of coupling chromatography and crystallization for efficient enantioseparations. Poster presented at 16th International Symposium, Exhibit & Workshops on Preparative / Process Chromatography (PREP 2003), San Francisco, USA.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0013-9F3B-A
Abstract
Within the pharmaceutical industry and in biotechnology there is an increasing need for selective and efficient separation technologies to isolate value added products with a high purity. A hybrid process approach consisting of chromatography and fractional crystallization is studied in detail. The work presented here is concerned with the application and evaluation of the concept of combing these processes to separate a given pharmaceutical intermediate. A comparison performing the same separation exclusively with a single chromatographic process will be given.