de.mpg.escidoc.pubman.appbase.FacesBean
Deutsch
 
Hilfe Wegweiser Impressum Kontakt Einloggen
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT

Freigegeben

Zeitschriftenartikel

Immunological outcomes of new tuberculosis vaccine trials: WHO panel recommendations

MPG-Autoren
http://pubman.mpdl.mpg.de/cone/persons/resource/persons82090

Parida,  Shreemanta K.
Department of Immunology, Max Planck Institute for Infection Biology, Max Planck Society;

Externe Ressourcen
Es sind keine Externen Ressourcen verfügbar
Volltexte (frei zugänglich)

PLoS_Med_2008_5_e145_1033.pdf
(Verlagsversion), 2MB

Ergänzendes Material (frei zugänglich)
Es sind keine frei zugänglichen Ergänzenden Materialien verfügbar
Zitation

Hanekom, W. A., Dockrell, H. M., Ottenhoff, T. H. M., Doherty, T. M., Fletcher, H., McShane, H., et al. (2008). Immunological outcomes of new tuberculosis vaccine trials: WHO panel recommendations. PLoS Medicine, 5(7): 145, pp. 1033-1036.


Zitierlink: http://hdl.handle.net/11858/00-001M-0000-000E-C1AE-7
Zusammenfassung
Summary Points * Many new and diverse tuberculosis vaccines are currently under development. * The ability to compare clinical immunogenicity between different candidates would be an important asset. * The World Health Organization (WHO) Initiative for Vaccine Research sponsored three meetings of experts to discuss assay harmonization for new tuberculosis vaccine trials. * We describe advantages and disadvantages of multiple T cell assay approaches and make specific recommendations for phase I/IIa trials. These include introducing a single and simple harmonised assay for all trials.