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Journal Article

Ion channels boost axonal injury in multiple sclerosis

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons38897

Hohlfeld,  Reinhard
Department: Neuroimmunology / Wekerle, MPI of Neurobiology, Max Planck Society;

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Citation

Hohlfeld, R. (2012). Ion channels boost axonal injury in multiple sclerosis. NATURE MEDICINE, 18(12), 1743-1745. doi:10.1038/nm.3021.


Cite as: http://hdl.handle.net/11858/00-001M-0000-000E-B97B-7
Abstract
In neuroinflammatory diseases such as multiple sclerosis, ion channels may fan the embers of neurodegeneration. A new study shows that the cation channel TRPM4 (transient receptor potential melastatin 4) crucially contributes to axonal loss in an animal model of multiple sclerosis (pages 1805-1811).