de.mpg.escidoc.pubman.appbase.FacesBean
Deutsch
 
Hilfe Wegweiser Impressum Kontakt Einloggen
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT

Freigegeben

Zeitschriftenartikel

Functional Specialization of Parallel Motion Detection Circuits in the Fly

MPG-Autoren
http://pubman.mpdl.mpg.de/cone/persons/resource/persons38912

Joesch,  Maximilian
Department: Systems and Computational Neurobiology / Borst, MPI of Neurobiology, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons39108

Weber,  Franz
Department: Systems and Computational Neurobiology / Borst, MPI of Neurobiology, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons38813

Eichner,  Hubert
Department: Systems and Computational Neurobiology / Borst, MPI of Neurobiology, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons38770

Borst,  Alexander
Department: Systems and Computational Neurobiology / Borst, MPI of Neurobiology, Max Planck Society;

Externe Ressourcen
Es sind keine Externen Ressourcen verfügbar
Volltexte (frei zugänglich)

902.full.pdf
(beliebiger Volltext), 376KB

Ergänzendes Material (frei zugänglich)
Es sind keine frei zugänglichen Ergänzenden Materialien verfügbar
Zitation

Joesch, M., Weber, F., Eichner, H., & Borst, A. (2013). Functional Specialization of Parallel Motion Detection Circuits in the Fly. JOURNAL OF NEUROSCIENCE, 33(3), 902-905. doi:10.1523/JNEUROSCI.3374-12.2013.


Zitierlink: http://hdl.handle.net/11858/00-001M-0000-000E-B644-C
Zusammenfassung
In the fly Drosophila melanogaster, photoreceptor input to motion vision is split into two parallel pathways as represented by first-order interneurons L1 and L2 (Rister et al., 2007; Joesch et al., 2010). However, how these pathways are functionally specialized remains controversial. One study (Eichner et al., 2011) proposed that the L1-pathway evaluates only sequences of brightness increments (ON-ON), while the L2-pathway processes exclusively brightness decrements (OFF-OFF). Another study (Clark et al., 2011) proposed that each of the two pathways evaluates both ON-ON and OFF-OFF sequences. To decide between these alternatives, we recorded from motion-sensitive neurons in flies in which the output from either L1 or L2 was genetically blocked. We found that blocking L1 abolishes ON-ON responses but leaves OFF-OFF responses intact. The opposite was true, when the output from L2 was blocked. We conclude that the L1 and L2 pathways are functionally specialized to detect ON-ON and OFF-OFF sequences, respectively.