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Journal Article

Occurrence of delusions during repetitive transcranial magnetic stimulation (rTMS) in major depression

MPS-Authors

Zwanzger,  P
Max Planck Institute of Psychiatry, Max Planck Society;

Ella,  R
Max Planck Institute of Psychiatry, Max Planck Society;

Keck,  ME
Max Planck Institute of Psychiatry, Max Planck Society;

Rupprecht,  R
Max Planck Institute of Psychiatry, Max Planck Society;

Padberg,  F
Max Planck Institute of Psychiatry, Max Planck Society;

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Citation

Zwanzger, P., Ella, R., Keck, M., Rupprecht, R., & Padberg, F. (2002). Occurrence of delusions during repetitive transcranial magnetic stimulation (rTMS) in major depression. Biological Psychiatry, 51(7), 602-603.


Cite as: http://hdl.handle.net/11858/00-001M-0000-000E-A217-6
Abstract
Background: Repetitive transcranial magnetic stimulation (rTMS) has been suggested as a potentially useful treatment for major depression. Nonpsychotic depressed patients appear to have a better outcome than those with psychotic symptoms. Methods: We report findings in a patient suffering from recurrent, nonpsychotic major depression (DSM-IV) who had 13 daily sessions of rTMS monotherapy within a 3 week period. Results: During rTMS treatment, the patient developed recurrent severe delusions, which he had never experienced before. Psychotic symptoms remitted quickly with neuroleptic medication. Conclusions: In light of preclinical findings showing increased dopaminergic activity after rTMS treatment, occurrence of psychotic symptoms should be considered a potential side effect of rTMS treatment. Biol Psychiatry 2002;51:602-603 (C) 2002 Society of Biological Psychiatr