Trait dissociation affects the behavioral response to cholecystokinin 
tetrapeptide in healthy man

Kellner, M; Yassouridis, A; Hua, Y; Wendrich, M; Naber, D; Wiedemann, K

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Trait dissociation affects the behavioral response to cholecystokinin tetrapeptide in healthy man

MPS-Authors

Kellner, M
Max Planck Institute of Psychiatry, Max Planck Society;

Yassouridis, A
Max Planck Institute of Psychiatry, Max Planck Society;

Hua, Y
Max Planck Institute of Psychiatry, Max Planck Society;

Wendrich, M
Max Planck Institute of Psychiatry, Max Planck Society;

Naber, D
Max Planck Institute of Psychiatry, Max Planck Society;

Wiedemann, K
Max Planck Institute of Psychiatry, Max Planck Society;

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Citation

Kellner, M., Yassouridis, A., Hua, Y., Wendrich, M., Naber, D., & Wiedemann, K. (2002). Trait dissociation affects the behavioral response to cholecystokinin tetrapeptide in healthy man. Psychiatry Research, 111(1), 93-96.

Cite as: https://hdl.handle.net/11858/00-001M-0000-000E-A199-8

Abstract

Trait dissociation might influence the response to panicogens in normal controls. The behavioral effects of 25 mug of cholecystokinin tetrapeptide (CCK-4) were studied in 18 healthy men, nine each with high or low trait dissociation. Subjects with high trait dissociation showed a significantly lower increase of acute dissociative, anxiety and panic symptoms compared with subjects with low trait dissociation. Trait dissociation should be assessed in further behavioral challenge studies as a potentially important covariate. (C) 2002 Elsevier Science Ireland Ltd. All rights reserve