Expression of the helix-loop-helix gene id3 in the zebrafish embryo

Dickmeis, Thomas; Rastegar, Sepand; Lam, Chen Sok; Aanstad, Pia; Clark, Matthew; Fischer, Nadine; Rosa, Frédéric; Korzh, Vladimir; Strähle, Uwe

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Expression of the helix-loop-helix gene id3 in the zebrafish embryo

MPS-Authors

Aanstad, Pia
Max Planck Society;

Clark, Matthew
Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Dickmeis, T., Rastegar, S., Lam, C. S., Aanstad, P., Clark, M., Fischer, N., et al. (2002). Expression of the helix-loop-helix gene id3 in the zebrafish embryo. Mechanisms of Development, 113(1), 99-102.

Cite as: https://hdl.handle.net/11858/00-001M-0000-0010-8C68-1

Abstract

Proteins of the Extramacrochaetae and Id subfamily of Helix-Loop-Helix (HLH) proteins are negative regulators of bHLH transcription factors. We cloned a cDNA from zebrafish which encodes a member of the id3 subfamily. High levels of transcripts accumulated in the germ ring and in the embryonic shield. Towards the end of gastrulation, Id3 was highly expressed in the anterior prechordal plate and hypoblast. At later stages, id3 expression was turned on and off in a large variety of tissues within short periods of time. These include the lateral mesoderm, the cornea, the lens, the brain, the neural crest, the retina and the fins.