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Journal Article

Role of Oct-4 during acquisition of developmental competence in mouse oocyte.

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons50054

Adjaye,  James
Molecular Embryology and Aging (James Adjaye), Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society;

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Citation

Zuccotti, M., Merico, V., Redi, C. A., Bellazzi, R., Adjaye, J., & Garagna, S. (2009). Role of Oct-4 during acquisition of developmental competence in mouse oocyte. Proceedings of the Tecnobios Procreazione Symposium 2008 and 3rd international Conference on ‘The Cryopreservation of the Human Oocyte', 57-62. Retrieved from http://www.rbmonline.com/4DCGI/Article/Detail?38%091%09=%204373%09.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0010-7CB9-0
Abstract
Knowledge of what determines the developmental competence of oocytes during folliculogenesis is poor. This review, through the analysis of the expression profile of developmentally competent or incompetent mouse oocytes, summarizes the results of recent studies showing that the Oct-4 transcription factor regulating the expression of Stella and Foxj2 at the Nanog locus could play a pivotal role in the establishment of the oocyte’s developmental competence.