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Thesis

Identification of functional modules in human protein interaction networks.

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Pentchev,  Konstantin
Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society;

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MasterArbeit_Pentchev.pdf
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Citation

Pentchev, K. (2010). Identification of functional modules in human protein interaction networks. Master Thesis, Freie Universität Berlin, Berlin.


Cite as: https://hdl.handle.net/11858/00-001M-0000-0010-7A6A-3
Abstract
The novel method proposed in this thesis is able to identify functional modules making use of large-scale interaction and expression data. While theveri tion of these subnetworks remains di ult, they identify sets of proteins, which may play a key role in the development of malignancies. The modules provide an attractive basis for further research and may provide new targets for drug development.