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Journal Article

Inheritance of the endoplasmic reticulum and Golgi apparatus

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons77707

Barr,  F. A.
Former Research Groups, Max Planck Institute of Biochemistry, Max Planck Society;

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Barr, F. A. (2002). Inheritance of the endoplasmic reticulum and Golgi apparatus. Current Opinion in Cell Biology, 14(4), 496-499.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0010-6E8E-1
Abstract
Yeast and mammalian cells use a variety of different mechanisms to ensure that the endoplasmic reticulum and Golgi apparatus are inherited by both daughter cells on cell division. In yeast, endoplasmic reticulum inheritance involves both active microtubule and passive actin-based mechanisms, while the Golgi is transported into the forming daughter cell by an active actin-based mechanism. Animal cells actively partition the endoplasmic reticulum and Golgi apparatus, but association with the mitotic spindle - rather than the actin cytoskeleton - appears to be the mechanism.