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Journal Article

The Hmong diaspora: Preserved South-East Asian genetic ancestry in French Guianese Asians

MPS-Authors
http://pubman.mpdl.mpg.de/cone/persons/resource/persons27681

Brucato,  Nicolas
Language and Genetics Department, MPI for Psycholinguistics, Max Planck Society;
UMR 5288 CNRS, Laboratoire d’Anthropologie Moléculaire et Imagerie de Synthèse (AMIS), Université Paul-Sabatier Toulouse III, Toulouse, France;

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Fulltext (public)

Brucato_CR_Biologies_2012.pdf
(Publisher version), 885KB

Supplementary Material (public)

Brucato_Add_File_1.doc
(Supplementary material), 918KB

Brucato_Add_File_2.doc
(Supplementary material), 132KB

Brucato_Add_File_3.doc
(Supplementary material), 233KB

Brucato_Add_File_4.doc
(Supplementary material), 80KB

Brucato_Add_File_5.doc
(Supplementary material), 244KB

Brucato_Add_File_6.doc
(Supplementary material), 184KB

Citation

Brucato, N., Mazières, S., Guitard, E., Giscard, P.-H., Bois, É., Larrouy, G., et al. (2012). The Hmong diaspora: Preserved South-East Asian genetic ancestry in French Guianese Asians. Comptes Rendus Biologies, 335, 698-707. doi:10.1016/j.crvi.2012.10.003.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0010-1A96-4
Abstract
The Hmong Diaspora is one of the widest modern human migrations. Mainly localised in South-East Asia, the United States of America, and metropolitan France, a small community has also settled the Amazonian forest of French Guiana. We have biologically analysed 62 individuals of this unique Guianese population through three complementary genetic markers: mitochondrial DNA (HVS-I/II and coding region SNPs), Y-chromosome (SNPs and STRs), and the Gm allotypic system. All genetic systems showed a high conservation of the Asian gene pool (Asian ancestry: mtDNA = 100.0%; NRY = 99.1%; Gm = 96.6%), without a trace of founder effect. When compared across various Asian populations, the highest correlations were observed with Hmong-Mien groups still living in South-East Asia (Fst < 0.05; P-value < 0.05). Despite a long history punctuated by exodus, the French Guianese Hmong have maintained their original genetic diversity.