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Journal Article

Signature of recent historical events in the European Y-chromosomal STR haplotype distribution

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http://pubman.mpdl.mpg.de/cone/persons/resource/persons72780

Kayser,  Manfred
Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society;

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Roewer, L., Croucher, P. J. P., Willuweit, S., Lu, T. T., Kayser, M., Lessig, R., et al. (2005). Signature of recent historical events in the European Y-chromosomal STR haplotype distribution. Human Genetics, 116(4), 279-291.


Cite as: http://hdl.handle.net/11858/00-001M-0000-0010-02E8-B
Abstract
Previous studies of human Y-chromosomal single-nucleotide polymorphisms (Y-SNPs) established a link between the extant Y-SNP haplogroup distribution and the prehistoric demography of Europe. By contrast, our analysis of seven rapidly evolving Y-chromosomal short tandem repeat loci (Y-STRs) in over 12,700 samples from 91 different locations in Europe reveals a signature of more recent historic events, not previously detected by other genetic markers. Cluster analysis based upon molecular variance yields two clearly identifiable sub-clusters of Western and Eastern European Y-STR haplotypes, and a diverse transition zone in central Europe, where haplotype spectra change more rapidly with longitude than with latitude. This and other observed patterns of Y-STR similarity may plausibly be related to particular historical incidents, including, for example, the expansion of the Franconian and Ottoman Empires. We conclude that Y-STRs may be capable of resolving male genealogies to an unparalleled degree and could therefore provide a useful means to study local population structure and recent demographic history. [References: 42]