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Journal Article

Real-time MRI: recent advances using radial FLASH.

MPS-Authors
http://pubman.mpdl.mpg.de/cone/persons/resource/persons15943

Uecker,  M.
Biomedical NMR Research GmbH, MPI for biophysical chemistry, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons16078

Zhang,  S.
Biomedical NMR Research GmbH, MPI for biophysical chemistry, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons15968

Voit,  D.
Biomedical NMR Research GmbH, MPI for biophysical chemistry, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons15516

Merboldt,  K. D.
Biomedical NMR Research GmbH, MPI for biophysical chemistry, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons15082

Frahm,  J.
Biomedical NMR Research GmbH, MPI for biophysical chemistry, Max Planck Society;

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Citation

Uecker, M., Zhang, S., Voit, D., Merboldt, K. D., & Frahm, J. (2012). Real-time MRI: recent advances using radial FLASH. Imaging in Medicine, 4(4), 461-476. doi:10.2217/iim.12.32.


Cite as: http://hdl.handle.net/11858/00-001M-0000-000F-F0F7-5
Abstract
Recent advances in real-time MRI result in high-quality images with acquisition times of only approximately 30 ms. The technique employs a fast low-angle shot sequence with proton density, T1 or T2/T1 contrast and radial data encoding for motion robustness. High temporal resolution is achieved by an up to 20-fold undersampling of the radial data. An iterative reconstruction algorithm estimates the image as the solution of a nonlinear inverse problem and ensures image fidelity by temporal regularization, which exploits the temporal continuity of successive frames during dynamic imaging. Preliminary real-time examinations at a field strength of 3T range from joint dynamics, speaking and swallowing to the 3D localization of objects in space. In particular, real-time MRI largely facilitates assessments of cardiovascular function and quantitative blood flow. Taken together, advanced real-time MRI methods allow for hitherto inaccessible studies, lead to more robust and shorter examinations, improve patient comfort and offer new diagnostic opportunities.