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Application of self-assembly techniques in the design of biocompatible protein microarray surfaces

MPS-Authors
http://pubman.mpdl.mpg.de/cone/persons/resource/persons48701

Schiller,  S.
MPI for Polymer Research, Max Planck Society;

http://pubman.mpdl.mpg.de/cone/persons/resource/persons48136

Kambhampati,  D.
MPI for Polymer Research, Max Planck Society;

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Citation

Schaeferling, M., Schiller, S., Paul, H., Kruschina, M., Pavlickova, P., Meerkamp, M., et al. (2002). Application of self-assembly techniques in the design of biocompatible protein microarray surfaces. Electrophoresis, 23(18), 3097-3105.


Cite as: http://hdl.handle.net/11858/00-001M-0000-000F-64FC-1
Abstract
This review focuses on the application of novel technologies for generating biocompatible surfaces for high-throughput screening (HTS) of proteins. Various methods of coupling and spotting proteins on self-assembled monolayer (SAM) surfaces will be described along with the protein chip challenges pertaining to spot homogeneity, morphology, biocompatibility and reproducibility.