de.mpg.escidoc.pubman.appbase.FacesBean
English
 
Help Guide Disclaimer Contact us Login
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Dendritic structural plasticity

MPS-Authors
http://pubman.mpdl.mpg.de/cone/persons/resource/persons39095

Tavosanis,  Gaia
Research Group: Dendrite Differentiation / Tavosanis, MPI of Neurobiology, Max Planck Society;
External Organizations;

Locator
There are no locators available
Fulltext (public)
There are no public fulltexts available
Supplementary Material (public)
There is no public supplementary material available
Citation

Tavosanis, G. (2012). Dendritic structural plasticity. DEVELOPMENTAL NEUROBIOLOGY, 72(1), 73-86. doi:10.1002/dneu.20951.


Cite as: http://hdl.handle.net/11858/00-001M-0000-000F-3C07-A
Abstract
Dendrites represent the compartment of neurons primarily devoted to collecting and computating input. Far from being static structures, dendrites are highly dynamic during development and appear to be capable of plastic changes during the adult life of animals. During development, it is a combination of intrinsic programs and external signals that shapes dendrite morphology; input activity is a conserved extrinsic factor involved in this process. In adult life, dendrites respond with more modest modifications of their structure to various types of extrinsic information, including alterations of input activity. Here, the author reviews classical and recent evidence of dendrite plasticity in invertebrates and vertebrates and current progress in the understanding of the molecular mechanisms that underlie this plasticity. Importantly, some fundamental questions such as the functional role of dendrite remodeling and the causal link between structural modifications of neurons and plastic processes, including learning, are still open. (c) 2011 Wiley Periodicals, Inc. Develop Neurobiol 72: 7386, 2012