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Detectability of the BOLD signal

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Goense,  J
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Merkle,  H
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Logothetis,  NK
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Goense, J., Merkle, H., & Logothetis, N. (2010). Detectability of the BOLD signal. Poster presented at ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden.


Cite as: https://hdl.handle.net/11858/00-001M-0000-0013-C06A-C
Abstract
The BOLD signal is a weak signal, and hence if no BOLD signal is found in an area this does not automatically mean there is no neural activity in that area. Signal dropout, artifacts, instability, physiological noise, RF-coil inhomogeneity etc. can all reduce the SNR locally leading to decreased detectability of the BOLD signal. Here we illustrate that calculation of the spatial distribution of the detection thresholds allows us to assign a degree of confidence to the activations as well as identify areas where detectability of functional activation is compromised.