Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT
  Expression profiles of the essential intermediate filament (IF) protein A2 and the IF protein C2 in the nematode Caenorhabditis elegans

Karabinos, A., Schulze, E., Klisch, T., Wang, J., & Weber, K. (2002). Expression profiles of the essential intermediate filament (IF) protein A2 and the IF protein C2 in the nematode Caenorhabditis elegans. Mechanisms of Development, 117(1-2), 311-314. Retrieved from http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6T9H-46572X4-1-9&_cdi=5115&_user=38661&_pii=S0925477302001922&_origin=search&_coverDate=09%2F30%2F2002&_sk=998829998&view=c&wchp=dGLzVlb-zSkWA&md5=973992c4b8f53bcbc41f5c49934f34fb&ie=/sdarticle.pdf.

Item is

Dateien

einblenden: Dateien
ausblenden: Dateien
:
16671.pdf (Verlagsversion), 0B
Name:
16671.pdf
Beschreibung:
-
OA-Status:
Sichtbarkeit:
Öffentlich
MIME-Typ / Prüfsumme:
application/pdf / [MD5]
Technische Metadaten:
Copyright Datum:
-
Copyright Info:
-
Lizenz:
-

Externe Referenzen

einblenden:

Urheber

einblenden:
ausblenden:
 Urheber:
Karabinos, A.1, Autor           
Schulze, E., Autor
Klisch, T., Autor
Wang, J.1, Autor           
Weber, K.1, Autor           
Affiliations:
1Department of Biochemistry and Cell Biology, MPI for biophysical chemistry, Max Planck Society, ou_578618              

Inhalt

einblenden:
ausblenden:
Schlagwörter: Caenorhabditis elegans; desmosomes; hypodermis; intermediate filament; promoter
 Zusammenfassung: The multigene family of intermediate filament (IF) proteins in Caenorhabditis elegans covers 11 members of which four (A1-3, B1) are essential for development. Suppression of a fifth gene (C2) results in a dumpy phenotype. Expression patterns of three essential genes (A1, A3, B1) were already reported. To begin to analyze the two remaining RNAi phenotypes we followed the expression of the A2 and C2 proteins. Expression of A2 mRNA starts in larval stage L1 and continues in the adult. Transgenic A2 promoter/gfp larvae strongly display GFP in the main body hypodermis but not in seam cells. This pattern and the muscle displacement/paralysis induced by RNAi silencing are consistent with the role of this protein in keeping the correct hypodermis/muscle relationship during development. IF protein C2 occurs in the cytoplasm and desmosomes of intestinal cells and in pharynx desmosomes. Expression of C2 starts in the late embryo and persists in all further stages. (C) 2002 Published by Elsevier Science Ireland Ltd.

Details

einblenden:
ausblenden:
Sprache(n): eng - English
 Datum: 2002-09
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Art des Abschluß: -

Veranstaltung

einblenden:

Entscheidung

einblenden:

Projektinformation

einblenden:

Quelle 1

einblenden:
ausblenden:
Titel: Mechanisms of Development
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: 117 (1-2) Artikelnummer: - Start- / Endseite: 311 - 314 Identifikator: -