English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Functional somatotopy of finger representations in human primary motor cortex

Dechent, P., & Frahm, J. (2003). Functional somatotopy of finger representations in human primary motor cortex. Human Brain Mapping, 18(4), 272-283. Retrieved from http://www3.interscience.wiley.com/cgi-bin/fulltext/103020944/PDFSTART.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Dechent, P.1, Author           
Frahm, J.1, Author           
Affiliations:
1Biomedical NMR Research GmbH, MPI for biophysical chemistry, Max Planck Society, ou_578634              

Content

show
hide
Free keywords: functional MRI; primary motor cortex; finger somatotopy; human
 Abstract: To assess the degree of fine-scale somatotopy within the hand area of the human primary motor cortex (M1), functional mapping of individual movements of all fingers was performed in healthy young subjects (n = 7) using MRI at 0.8 x 0.8 mm(2) resolution and 4 mm section thickness. The experimental design comprised both a direct paradigm contrasting single digit movements vs. motor rest and multiple differential paradigms contrasting single digit movements vs. the movement of another digit. Direct mapping resulted in largely overlapping activations. A somatotopic arrangement was only recognizable when considering the mean center-of-mass coordinates of individual digit representations averaged across subjects. In contrast, differential paradigms revealed more segregated and somatotopically ordered activations in single subjects. The use of center-of-mass coordinates yielded inter-digit distances ranging from 2.0 to 16.8 mm, which reached statistical significance for pairs of more distant digits. For the middle fingers, the functional somatotopy obtained by differential mapping was dependent on the choice of the digit used for control. These results confirm previous concepts that finger somatotopy in the human M1 hand area emerges as a functional predominance of individual digit representations sharing common areas in a distributed though ordered network. Hum. Brain Mapping 18:272-283, 2003. (C) 2003 Wiley-Liss, Inc.

Details

show
hide
Language(s): eng - English
 Dates: 2003-04
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Human Brain Mapping
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 18 (4) Sequence Number: - Start / End Page: 272 - 283 Identifier: -