Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT
  Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia

Tucci, S., Vohr, S. H., McCoy, R. C., Vernot, B., Robinson, M. R., Barbieri, C., et al. (2018). Evolutionary history and adaptation of a human pygmy population of Flores Island, Indonesia. Science, 361(6401), 511-516. doi:10.1126/science.aar8486.

Item is

Basisdaten

einblenden: ausblenden:
Genre: Zeitschriftenartikel

Dateien

einblenden: Dateien
ausblenden: Dateien
:
shh1040.pdf (Verlagsversion), 9MB
 
Datei-Permalink:
-
Name:
shh1040.pdf
Beschreibung:
DOI funktioniert niccht. Stand 07.08.18
OA-Status:
Sichtbarkeit:
Privat
MIME-Typ / Prüfsumme:
application/pdf
Technische Metadaten:
Copyright Datum:
-
Copyright Info:
-
Lizenz:
-

Externe Referenzen

einblenden:

Urheber

einblenden:
ausblenden:
 Urheber:
Tucci, Serena1, Autor
Vohr, Samuel H., Autor
McCoy, Rajiv C., Autor
Vernot, Benjamin, Autor
Robinson, Matthew R., Autor
Barbieri, Chiara1, Autor           
Nelson, Brad J., Autor
Fu, Wenqing, Autor
Purnomo, Gludhug A., Autor
Sudoyo, Herawati, Autor
Eichler, Evan E., Autor
Barbujani, Guido, Autor
Visscher, Peter M., Autor
Akey, Joshua M., Autor
Green, Richard E., Autor
Affiliations:
1Linguistic and Cultural Evolution, Max Planck Institute for the Science of Human History, Max Planck Society, ou_2074311              

Inhalt

einblenden:
ausblenden:
Schlagwörter: -
 Zusammenfassung: Flores Island in Indonesia has a long history of hominin occupation, including by the extinct Homo floresiensis and a more recent settlement by modern humans. Furthermore, Flores has an extant population of pygmy humans, and H. floresiensis exhibited a diminutive adult size relative to other hominins. Tucci et al. examined genetic variation among 32 individuals, including 10 sequenced genomes, from a population of pygmies living close to the cave where H. floresiensis remains were discovered. These individuals exhibit signatures of polygenic selection explaining the short stature and have genomic content from both Neanderthals and Denisovans, but no additional archaic lineages. Thus, restricted height is under selection at this location and has evolved independently at least twice in hominins.Science, this issue p. 511Flores Island, Indonesia, was inhabited by the small-bodied hominin species Homo floresiensis, which has an unknown evolutionary relationship to modern humans. This island is also home to an extant human pygmy population. Here we describe genome-scale single-nucleotide polymorphism data and whole-genome sequences from a contemporary human pygmy population living on Flores near the cave where H. floresiensis was found. The genomes of Flores pygmies reveal a complex history of admixture with Denisovans and Neanderthals but no evidence for gene flow with other archaic hominins. Modern individuals bear the signatures of recent positive selection encompassing the FADS (fatty acid desaturase) gene cluster, likely related to diet, and polygenic selection acting on standing variation that contributed to their short-stature phenotype. Thus, multiple independent instances of hominin insular dwarfism occurred on Flores.

Details

einblenden:
ausblenden:
Sprache(n): eng - English
 Datum: 2018-08-03
 Publikationsstatus: Online veröffentlicht
 Seiten: 8
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: 10.1126/science.aar8486
Anderer: shh1040
 Art des Abschluß: -

Veranstaltung

einblenden:

Entscheidung

einblenden:

Projektinformation

einblenden:

Quelle 1

einblenden:
ausblenden:
Titel: Science
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: Washington, D.C. : American Association for the Advancement of Science
Seiten: - Band / Heft: 361 (6401) Artikelnummer: - Start- / Endseite: 511 - 516 Identifikator: ISSN: 0036-8075
CoNE: https://pure.mpg.de/cone/journals/resource/991042748276600_1