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  From improved diagnostics to presurgical planning : high-resolution functionally graded multimaterial 3D printing of biomedical tomographic data sets

Hosny, A., Keating, S. J., Dilley, J. D., Ripley, B., Kelil, T., Pieper, S., et al. (2018). From improved diagnostics to presurgical planning: high-resolution functionally graded multimaterial 3D printing of biomedical tomographic data sets. 3D Printing and Additive Manufacturing, 5(2), 103-113. doi:10.1089/3dp.2017.0140.

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 Urheber:
Hosny, Ahmed, Autor
Keating, Steven J., Autor
Dilley, Joshua D., Autor
Ripley, Beth, Autor
Kelil, Tatiana, Autor
Pieper, Steve, Autor
Kolb, Dominik, Autor
Bader, Christoph, Autor
Pobloth, Anne-Marie, Autor
Griffin, Molly, Autor
Nezafat, Reza, Autor
Duda, Georg, Autor
Chiocca, Ennio A., Autor
Stone, James R., Autor
Michaelson, James S., Autor
Dean, Mason N.1, Autor           
Oxman, Neri, Autor
Weaver, James C., Autor
Affiliations:
1Mason Dean (Indep. Res.), Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_2231639              

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 Zusammenfassung: Three-dimensional (3D) printing technologies are increasingly used to convert medical imaging studies into tangible (physical) models of individual patient anatomy, allowing physicians, scientists, and patients an unprecedented level of interaction with medical data. To date, virtually all 3D-printable medical data sets are created using traditional image thresholding, subsequent isosurface extraction, and the generation of .stl surface mesh file formats. These existing methods, however, are highly prone to segmentation artifacts that either over- or underexaggerate the features of interest, thus resulting in anatomically inaccurate 3D prints. In addition, they often omit finer detailed structures and require time- and labor-intensive processes to visually verify their accuracy. To circumvent these problems, we present a bitmap-based multimaterial 3D printing workflow for the rapid and highly accurate generation of physical models directly from volumetric data stacks. This workflow employs a thresholding-free approach that bypasses both isosurface creation and traditional mesh slicing algorithms, hence significantly improving speed and accuracy of model creation. In addition, using preprocessed binary bitmap slices as input to multimaterial 3D printers allows for the physical rendering of functional gradients native to volumetric data sets, such as stiffness and opacity, opening the door for the production of biomechanically accurate models.

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Sprache(n): eng - English
 Datum: 2018-05-292018
 Publikationsstatus: Erschienen
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 Identifikatoren: DOI: 10.1089/3dp.2017.0140
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Titel: 3D Printing and Additive Manufacturing
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: New Rochelle, NY : Mary Ann Liebert
Seiten: - Band / Heft: 5 (2) Artikelnummer: - Start- / Endseite: 103 - 113 Identifikator: ISSN: 2329-7662