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  Improved preparation of vaccines against Streptococcus pneumoniae type 3
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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-002E-1866-2 Version Permalink: http://hdl.handle.net/21.11116/0000-0000-63E5-E
Genre: Patent

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Patent.pdf (Publisher version), 3MB
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 Creators:
Seeberger, Peter H.1, Author              
Pereira, Claney Lebev2, Author              
Parameswarappa, Sharavathi Guddehalli2, Author              
Calow, Adam D. J.2, Author              
Menova, Petra2, Author              
Baek, Ju Yuel2, Author              
Affiliations:
1Peter H. Seeberger, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, escidoc:2040285              
2Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, escidoc:1863308              

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 Abstract: The present invention relates to the preparation of a synthetic tetrasaccharide representing part of the repeating unit of the Streptococcus pneumoniae type 3 capsular polysaccharide as well as conjugates thereof. Said conjugates are particularly useful for prevention and/or treatment of diseases associated with Streptococcus pneumoniae, and more specifically of diseases associated with Streptococcus pneumoniae type 3. The disclosed synthetic method has the huge advantages over the state of the art synthetic methods that intermediate products are crystalline, coupling reaction yields are higher, less reaction steps are required and purification of intermediate products is easier.

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 Dates: 2016-04-152017-10-18
 Publication Status: Published online
 Pages: -
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 Identifiers: Patent Application Nr.: EP20160165694
Patent Publication Nr.: EP3231810
 Degree: -

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