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  Vaccines against Streptococcus pneumoniae serotype 5

Chakkumkal, A., Lisboa, M., Martin, C. E., Pereira, C. L., Seeberger, P. H., & Khan, N.(2016). Vaccines against Streptococcus pneumoniae serotype 5.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-002C-428E-B Version Permalink: https://hdl.handle.net/21.11116/0000-0006-5979-F
Genre: Patent

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2382998.pdf (Publisher version), 8MB
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 Creators:
Chakkumkal, Anish1, Author           
Lisboa, Marilda2, Author
Martin, Christopher E.2, Author           
Pereira, Claney Lebev2, Author           
Seeberger, Peter H.2, Author           
Khan, Naeem3, Author           
Affiliations:
1Chakkumal Anish, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863299              
2Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863308              
3Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863286              

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 Abstract: The present invention relates to well-defined synthetic saccharides of general formula (I) that are related to the repeating unit of Streptococcus pneumoniae serotype 5 capsular polysaccharide and conjugates thereof. The conjugates and pharmaceutical compositions containing said conjugates are useful for prevention and/or treatment of diseases associated with Streptococcus pneumoniae, and more specifically against diseases associated with Streptococcus pneumoniae serotype 5. Furthermore, the synthetic saccharides of general formula (I) are useful as marker in immunological assays for detection of antibodies against Streptococcus pneumoniae bacteria.

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 Dates: 2015-06-082016-12-15
 Publication Status: Published online
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 Identifiers: Patent Publication Nr.: PCT/EP2016/051608
Patent Nr.: WO2016198170
Patent Application Nr.: EP15171079
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