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  Ptychographic coherent diffractive imaging of weakly scattering specimens

Dierolf, M., Thibault, P., Menzel, A., Kewish, C. M., Jefimovs, K., Schlichting, I., et al. (2010). Ptychographic coherent diffractive imaging of weakly scattering specimens. New Journal of Physics, 12(3), 35017-3530. doi:10.1088/1367-2630/12/3/035017.

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Genre: Journal Article
Alternative Title : Ptychographic coherent diffractive imaging of weakly scattering specimens

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Dierolf, Martin, Author
Thibault, Pierre, Author
Menzel, Andreas, Author
Kewish, Cameron M., Author
Jefimovs, Konstantins, Author
Schlichting, Ilme1, Author           
von König, Konstanze1, Author           
Bunk, Oliver, Author
Pfeiffer, Franz, Author
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1Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Max Planck Society, ou_1497700              

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 Abstract: Applying iterative phase retrieval schemes to ptychographic data, i.e. diffraction patterns collected with a localized illumination probe from overlapping regions of a specimen, has enabled the investigation of extended specimens previously inaccessible by other coherent x-ray diffractive imaging methods. While the technique had initially been limited by the requirement of precise knowledge of the illumination function, recent algorithmic developments allow now the simultaneous reconstruction of both the probe and the object. However, these new approaches suffer from an inherent ambiguity, which affects especially the case of weakly scattering specimens. We present new schemes to circumvent this problem and introduce new tools for obtaining information about the scattering behaviour of weak phase objects already during data collection. The new techniques are experimentally demonstrated for a data set taken on Magnetospirillum gryphiswaldense. Applying iterative phase retrieval schemes to ptychographic data, i.e. diffraction patterns collected with a localized illumination probe from overlapping regions of a specimen, has enabled the investigation of extended specimens previously inaccessible by other coherent x−ray diffractive imaging methods. While the technique had initially been limited by the requirement of precise knowledge of the illumination function, recent algorithmic developments allow now the simultaneous reconstruction of both the probe and the object. However, these new approaches suffer from an inherent ambiguity, which affects especially the case of weakly scattering specimens. We present new schemes to circumvent this problem and introduce new tools for obtaining information about the scattering behaviour of weak phase objects already during data collection. The new techniques are experimentally demonstrated for a data set taken on Magnetospirillum gryphiswaldense

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Language(s): eng - English
 Dates: 2009-12-292010-03-31
 Publication Status: Issued
 Pages: 15
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 Table of Contents: -
 Rev. Type: Peer
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Title: New Journal of Physics
  Alternative Title : New J. Phys.
Source Genre: Journal
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Publ. Info: Bristol : IOP Publishing
Pages: - Volume / Issue: 12 (3) Sequence Number: - Start / End Page: 35017 - 3530 Identifier: ISSN: 1367-2630
CoNE: https://pure.mpg.de/cone/journals/resource/954926913666