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  New technologies for DNA analysis - a review of the READNA Project.

McGinn, S., Bauer, D., Bretfort, T., Mertes, F., Lehrach, H., & Sauer, S. (2016). New technologies for DNA analysis - a review of the READNA Project. New biotechnology, 33(3), 311-330. doi:10.1016/j.nbt.2015.10.003.

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2015-01-01
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 Creators:
McGinn, Steven1, Author
Bauer, David2, Author
Bretfort, Thomas3, Author
Mertes, Florian4, Author           
Lehrach, Hans4, Author           
Sauer, Sascha5, Author           
Affiliations:
1CEA – Centre National de Génotypage, 2, rue Gaston Cremieux, 91057 Evry Cedex, France, ou_persistent22              
2The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK, ou_persistent22              
3Comprehensive Biomarker Center GmbH , Im Neuenheimer Feld 583, D-69120 Heidelberg, Germany, ou_persistent22              
4Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1433550              
5Nutrigenomics and Gene Regulation (Sascha Sauer), Independent Junior Research Groups (OWL), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1479662              

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Free keywords: Discovery of ‘TUF’ DNA – unusually difficult to denature stretches of genomic DNA sequence. Enrichment methods – new methods, benchmarking and descriptors of enrichment technologies. Manipulating, visualizing and interrogating individual DNA molecules in nanosystems. Nanopore Sequencing – first commercial nanopore sequencer from Oxford Nanopore Technologies.
 Abstract: e REvolutionary Approaches and Devices for Nucleic Acid analysis (READNA) project received funding from the European Commission for 41/2 years. The objectives of the project revolved around technological developments in nucleic acid analysis. The project partners have discovered, created and developed a huge body of insights into nucleic acid analysis, ranging from improvements and implementation of current technologies to the most promising sequencing technologies that constitute a 3(rd) and 4(th) generation of sequencing methods with nanopores and in situ sequencing, respectively.

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Language(s): eng - English
 Dates: 2015-10-162016-05-25
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1016/j.nbt.2015.10.003
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Title: New biotechnology
  Other : Biotechnol. Prog.
Source Genre: Journal
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Publ. Info: New York, NY : American Institute of Chemical Engineers
Pages: 19 Volume / Issue: 33 (3) Sequence Number: - Start / End Page: 311 - 330 Identifier: ISSN: 8756-7938
CoNE: https://pure.mpg.de/cone/journals/resource/954925627362