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  Type II toxin: antitoxin systems. More than small selfish entities?

Rocker, A., & Meinhart, A. (2016). Type II toxin: antitoxin systems. More than small selfish entities? Current Genetics, 62(2), 287-290. doi:10.1007/s00294-015-0541-7.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0029-2E7E-2 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-002A-328F-0
Genre: Journal Article

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CurrGenet_epub_2015_41-7.pdf (Any fulltext), 259KB
 
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http://dx.doi.org/10.1007/s00294-015-0541-7 (Any fulltext)
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http://link.springer.com/content/pdf/10.1007%2Fs00294-015-0541-7.pdf (Any fulltext)
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 Creators:
Rocker, Andrea1, Author           
Meinhart, Anton1, Author           
Affiliations:
1Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Max Planck Society, ou_1497700              

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Free keywords: Toxin–antitoxin system; Fusion; Multi-domain protein; Elongated toxin
 Abstract: Toxin-antitoxin (TA) modules regulate metabolism and viability of bacteria and archaea. In type II TA systems these functions are generally thought to be performed by two small proteins. However, evidence is increasing that the toxins are much more diverse and can form multi-domain proteins. Recently, we published a novel type II TA system in which toxin and antitoxin are covalently linked into a single polypeptide chain. In this review we summarize the current knowledge on these elongated toxin homologs and provide perspectives for future study.

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Language(s): eng - English
 Dates: 2015-11-072015-11-092015-11-232016-05-01
 Publication Status: Issued
 Pages: 3
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1007/s00294-015-0541-7
URI: http://www.ncbi.nlm.nih.gov/pubmed/26597447
URI: http://link.springer.com/article/10.1007%2Fs00294-015-0541-7
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Title: Current Genetics
  Other : Curr. Genet.
Source Genre: Journal
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Publ. Info: Heidelberg : Springer
Pages: - Volume / Issue: 62 (2) Sequence Number: - Start / End Page: 287 - 290 Identifier: ISSN: 0172-8083
CoNE: https://pure.mpg.de/cone/journals/resource/954925486761