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  Increased titer and reduced lactate accumulation in recombinant retrovirus production through the down-regulation of HIF1 and PDK

Rodrigues, A. F., Guerreiro, M. R., Formas-Oliveira, A. S., Fernandes, P., Blechert, A.-K., Genzel, Y., et al. (2016). Increased titer and reduced lactate accumulation in recombinant retrovirus production through the down-regulation of HIF1 and PDK. Biotechnology and Bioengineering, 113(1), 150-162. doi:10.1002/bit.25691.

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 Creators:
Rodrigues, A. F.1, 2, Author
Guerreiro , M. R.1, 2, Author
Formas-Oliveira, A. S.1, 2, Author
Fernandes, P.1, 2, Author
Blechert, Anne-Kareen3, Author           
Genzel, Yvonne3, Author           
Alves, P.M.1, 2, Author
Hu , W.S.4, Author
Coroadinha, A.S.1, 2, Author
Affiliations:
1iBET – Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal, ou_persistent22              
2Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Av. da República, Oeiras, Portugal, ou_persistent22              
3Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society, ou_1738140              
4Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, ou_persistent22              

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 Dates: 2016
 Publication Status: Issued
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 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1002/bit.25691
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Title: Biotechnology and Bioengineering
Source Genre: Journal
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Pages: - Volume / Issue: 113 (1) Sequence Number: - Start / End Page: 150 - 162 Identifier: -