Toward unsupervised single-shot diffractive imaging of heterogeneous particles 
using X-ray free-electron lasers

Park, Hyung Joo; Loh, N. Duane; Sierra, Raymond G.; Hampton, Christina Y.; Starodub, Dmitri; Martin, Andrew V.; Barty, Anton; Aquila, Andrew; Schulz, Joachim; Steinbrener, Jan F.; Shoeman, Robert L.; Lomb, Lukas; Kassemeyer, Stephan; Bostedt, Christoph; Bozek, John; Epp , Sascha W.; Erk, Benjamin; Hartmann, Robert; Rolles, Daniel; Rudenko, Artem; Rudek, Benedikt; Foucar, Lutz; Kimmel, Nils; Weidenspointner, Georg; Hauser, Guenter; Holl, Peter; Pedersoli, Emanuele; Liang, Mengning; Hunter, Mark S.; Gumprecht, Lars; Coppola, Nicola; Wunderer, Cornelia; Graafsma, Heinz; Maia, Filipe R.N.C.; Ekeberg, Tomas; Hantke, Max; Fleckenstein, Holger; Hirsemann, Helmut; Nass, Karol; Tobias, Herbert J.; Farquar, George R.; Benner, W. Henry; Hau-Riege, Stefan; Reich, Christian; Hartmann, Andreas; Soltau, Heike; Marchesini, Stefano; Bajt, Sasa; Barthelmess, Miriam; Strueder, Lothar; Ullrich, Joachim; Bucksbaum, Philip; Frank, Matthias; Schlichting, Ilme; Chapman, Henry N.; Bogan, Michael J.; Elser, Veit

doi:10.1364/OE.21.028729

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Toward unsupervised single-shot diffractive imaging of heterogeneous particles using X-ray free-electron lasers

Park, H. J., Loh, N. D., Sierra, R. G., Hampton, C. Y., Starodub, D., Martin, A. V., et al. (2013). Toward unsupervised single-shot diffractive imaging of heterogeneous particles using X-ray free-electron lasers. Optics Express, 21(23), 28729-28742. doi:10.1364/OE.21.028729.

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Park, Hyung Joo, Author
Loh, N. Duane, Author
Sierra, Raymond G., Author
Hampton, Christina Y., Author
Starodub, Dmitri, Author
Martin, Andrew V., Author
Barty, Anton, Author
Aquila, Andrew, Author
Schulz, Joachim, Author
Steinbrener, Jan F.¹, Author
Shoeman, Robert L.¹, Author
Lomb, Lukas¹, Author
Kassemeyer, Stephan¹, Author
Bostedt, Christoph, Author
Bozek, John, Author
Epp , Sascha W., Author
Erk, Benjamin¹, Author
Hartmann, Robert, Author
Rolles, Daniel¹, Author
Rudenko, Artem, Author
Rudek, Benedikt¹, Author         Foucar, Lutz¹, Author         Kimmel, Nils, AuthorWeidenspointner, Georg, AuthorHauser, Guenter, AuthorHoll, Peter, AuthorPedersoli, Emanuele, AuthorLiang, Mengning, AuthorHunter, Mark S., AuthorGumprecht, Lars, AuthorCoppola, Nicola, AuthorWunderer, Cornelia, AuthorGraafsma, Heinz, AuthorMaia, Filipe R.N.C., AuthorEkeberg, Tomas, AuthorHantke, Max, AuthorFleckenstein, Holger, AuthorHirsemann, Helmut, AuthorNass, Karol¹, Author         Tobias, Herbert J., AuthorFarquar, George R., AuthorBenner, W. Henry, AuthorHau-Riege, Stefan, AuthorReich, Christian, AuthorHartmann, Andreas, AuthorSoltau, Heike, AuthorMarchesini, Stefano, AuthorBajt, Sasa, AuthorBarthelmess, Miriam, AuthorStrueder, Lothar, AuthorUllrich, Joachim, AuthorBucksbaum, Philip, AuthorFrank, Matthias, AuthorSchlichting, Ilme¹, Author         Chapman, Henry N., AuthorBogan, Michael J., AuthorElser, Veit, Author more..

Affiliations:
1Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Max Planck Society, ou_1497700

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Abstract: Single shot diffraction imaging experiments via X-ray free-electron lasers can generate as many as hundreds of thousands of diffraction patterns of scattering objects. Recovering the real space contrast of a scattering object from these patterns currently requires a reconstruction process with user guidance in a number of steps, introducing severe bottlenecks in data processing. We present a series of measures that replace user guidance with algorithms that reconstruct contrasts in an unsupervised fashion. We demonstrate the feasibility of automating the reconstruction process by generating hundreds of contrasts obtained from soot particle diffraction experiments

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Language(s): eng - English

Dates: Modified: 2013-10-26Submitted: 2013-08-19Accepted: 2013-10-27Published Online: 2013-11-14Date issued: 2013-11-18

Publication Status: Issued

Pages: 14

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Rev. Type: Peer

Identifiers: DOI: 10.1364/OE.21.028729
Other: 7966

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Title: Optics Express

Source Genre: Journal

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Pages: - Volume / Issue: 21 (23) Sequence Number: - Start / End Page: 28729 - 28742 Identifier: ISSN: 1094-4087
CoNE: https://pure.mpg.de/cone/journals/resource/954925609918