Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene 
product p21 complexed with GTP analogues

Scherer, Anna; John, Jacob; Linke, R.; Goody, Roger S.; Wittinghofer, Alfred; Pai, Emil F.; Holmes, Kenneth C.

doi:10.1016/0022-2836(89)90540-8

Local TagsRelease HistoryDetailsSummary

Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene product p21 complexed with GTP analogues

Scherer, A., John, J., Linke, R., Goody, R. S., Wittinghofer, A., Pai, E. F., et al. (1989). Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene product p21 complexed with GTP analogues. Journal of Molecular Biology (London), 206(1), 257-259. doi:10.1016/0022-2836(89)90540-8.

Item is Released

show all hide all

Basic

show hide

Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0019-ADD4-A Version Permalink: https://hdl.handle.net/21.11116/0000-0000-8DC8-0

Genre: Journal Article

Files

show Files

hide Files

:

JMolBiol_206_1989_257.pdf (Any fulltext), 286KB

File Permalink:
-

Name:
JMolBiol_206_1989_257.pdf

Description:
-

OA-Status:

Visibility:
Restricted (Max Planck Institute for Medical Research, MHMF; )

MIME-Type / Checksum:
application/pdf

Technical Metadata:

Copyright Date:
-

Copyright Info:
-

License:
-

Locators

show

hide

Locator:
https://www.sciencedirect.com/science/article/pii/0022283689905408/pdf?md5=4a6733900a32f0cfe2945904b093b951&pid=1-s2.0-0022283689905408-main.pdf (Any fulltext) Open Access status unknown

Description:
-

OA-Status:

Locator:
https://doi.org/10.1016/0022-2836(89)90540-8 (Any fulltext) Open Access status unknown

Description:
-

OA-Status:

Creators

show

hide

Creators:
Scherer, Anna¹, Author
John, Jacob, Author
Linke, R., Author
Goody, Roger S.², Author
Wittinghofer, Alfred², Author
Pai, Emil F., Author
Holmes, Kenneth C.^{2, 3, 4}, Author

Affiliations:
1Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Max Planck Society, ou_1497700
2Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497712
3Protein Cristallography XDS, Max Planck Institute for Medical Research, Max Planck Society, ou_1497735
4Muscle Research, Max Planck Institute for Medical Research, Max Planck Society, ou_1497731

Content

show

hide

Free keywords: -

Abstract: The catalytic domain (amino acid residues 1 to 166) of the human ras-oncogene product p21 complexed with the GTP analogues beta,gamma-imido-GTP (GMPPNP), beta,gamma-methylene-GTP (GMPPCP), and guanosine-5'-(gamma-thiotriphosphate) (GTP gamma S) have been been crystallized. Crystals of the GMPPNP and GMPPCP complexes are well suited for high resolution X-ray crystallography. They belong to space group P3(1)21 (or its enantiomorph P3(2)21) with unit cell axes a=b=40.3 A and c = 162.2 A.

Details

show

hide

Language(s): eng - English

Dates: Submitted: 1988-08-25Accepted: 1988-10-31Published Online: 2004-10-28Date issued: 1989-03-05

Publication Status: Issued

Pages: 3

Publishing info: -

Table of Contents: -

Rev. Type: Peer

Identifiers: DOI: 10.1016/0022-2836(89)90540-8
URI: https://www.ncbi.nlm.nih.gov/pubmed/2649686

Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show

hide

Title: Journal of Molecular Biology (London)

Other : J Mol Biol

Source Genre: Journal

Creator(s):

Affiliations:

Publ. Info: London : Academic Press

Pages: - Volume / Issue: 206 (1) Sequence Number: - Start / End Page: 257 - 259 Identifier: ISSN: 0022-2836
CoNE: https://pure.mpg.de/cone/journals/resource/954922646042