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Beginning six months from the full-issue publication date, or immediately upon publication for articles that carry the journal’s Open Access icon, articles published in Genome Research are distributed under a Creative Commons License (Attribution-NonCommercial 3.0 Unported License), as described at http://creativecommons.org/licenses/by-nc/3.0/. This license permits non-commercial use, including reproduction, adaptation, and distribution of the article provided the original author and source are credited.