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  The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: characterisation of an aminotransferase involved in the formation of 2-deoxystreptamine

Huang, F. L., Haydock, S. F., Mironenko, T., Spiteller, D., Li, Y. Y., & Spencer, J. B. (2005). The neomycin biosynthetic gene cluster of Streptomyces fradiae NCIMB 8233: characterisation of an aminotransferase involved in the formation of 2-deoxystreptamine. Organic and Biomolecular Chemistry, 3(8), 1410-1418.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0012-A0EA-6 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0012-A0EB-4
Genre: Journal Article

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 Creators:
Huang, F. L., Author
Haydock, S. F., Author
Mironenko, T., Author
Spiteller, D.1, Author           
Li, Y. Y., Author
Spencer, J. B., Author
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1Department of Bioorganic Chemistry, MPI for Chemical Ecology, Max Planck Society, ou_24028              

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Free keywords: Aminoglycoside antibiotics Aminocyclitol antibiotics Nucleotide-sequence Bacillus-circulans Coelicolor a3(2) L-glutamine Rna Identification Cloning Pathway Chemistry & Analysis in Current Contents(R)/Life Sciences Organic Chemistry/Polymer Science in Current Contents(R)/Physical, Chemical & Earth Sciences
 Abstract: The biosynthetic gene cluster of the 2-deoxystreptamine (DOS)-containing aminoglycoside antibiotic neomycin has been cloned for the first time by screening of a cosmid library of Streptomyces fradiae NCIMB 8233. Sequence analysis has identified 21 putat

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 Dates: 2005
 Publication Status: Issued
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 Identifiers: Other: BOL381
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Title: Organic and Biomolecular Chemistry
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Source Genre: Journal
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Pages: - Volume / Issue: 3 (8) Sequence Number: - Start / End Page: 1410 - 1418 Identifier: -