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  31P−NMR spectra of the Ha−ras p21. Nucleotide complexes

Rösch, P., Wittinghofer, A., Tucker, J., Sczakiel, G., Lebermann, R., & Schlichting, I. (1986). 31P−NMR spectra of the Ha−ras p21. Nucleotide complexes. Biochemical and Biophysical Research Communications, 135(2), 549-555. doi:10.1016/0006-291X(86)90029-X.

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Genre: Journal Article
Alternative Title : 31P−NMR spectra of the Ha−ras p21. Nucleotide complexes

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 Creators:
Rösch, Paul1, Author           
Wittinghofer, Alfred1, Author           
Tucker, J., Author
Sczakiel, Georg1, Author           
Lebermann, Reuben, Author
Schlichting, Ilme1, 2, Author           
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1Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497712              
2Photoreceptors, Max Planck Institute for Medical Research, Max Planck Society, ou_1856341              

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 Abstract: Phosphorus nuclear magnetic resonance spectra of the Ha−ras oncogene product p21 and its nucleotide complexes have been obtained. It is shown that the 31P nuclear magnetic resonance spectra of a number of nucleotide−enzyme complexes show some common features. In particular, the chemical shift values of the −phosphorus resonance of enzyme−bound NTP and NDP (N=A,G) of hydrolases exhibit a downfield shift virtually identical for myosin, elongation factor Tu, and the Ha−ras oncogene product p21. This suggests that the stereochemistry around the −phosphorus might be similar in these compoun

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Title: Biochemical and Biophysical Research Communications
  Alternative Title : Biochem. Biophys. Res. Commun.
Source Genre: Journal
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Pages: - Volume / Issue: 135 (2) Sequence Number: - Start / End Page: 549 - 555 Identifier: -