非表示:
キーワード:
homogeneous catalysis; marine natural products; NMR spectroscopy; structure elucidation; total synthesis
要旨:
Out of options? Even though a systematic approach was chosen, which led to a set of four diastereomeric macrolides modeled around the proposed structure of leiodolide B (see picture), the puzzle concerning the stereostructure of this cytotoxic metabolite derived from a deep-sea sponge still remains unsolved.
