English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Asymmetric synthesis of highly functionalized tetracyclic indole bases embodying the basic skeleton of yohimbine- and reserpine type alkaloids

Lock, R., & Waldmann, H. (1996). Asymmetric synthesis of highly functionalized tetracyclic indole bases embodying the basic skeleton of yohimbine- and reserpine type alkaloids. TETRAHEDRON LETTERS, 37(16), 2753-2756. doi:10.1016/0040-4039(96)00388-7.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Lock, R1, Author
Waldmann, Herbert2, Author           
Affiliations:
1external, ou_persistent22              
2Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society, ou_1753290              

Content

show
hide
Free keywords: -
 Abstract: Schiff bases derived from tryptophan methyl ester react with differently substituted electron-rich siloxy dienes in the presence of achiral or chiral boric acid esters to give enaminones 5 and 6 with high diastereomer ratios (up to >98:2). These intermediates are converted into highly functionalized indoloquinolizines 14 and 15 by means of a new method which employs the transformation of vinylogous amides to vinylogous chloromethyl amines and their subsequent conversion to vinylogous imidoyl chlorides as the key step. Copyright (C) 1996 Elsevier Science Ltd.

Details

show
hide
Language(s): eng - English
 Dates: 1996
 Publication Status: Issued
 Pages: 4
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: TETRAHEDRON LETTERS
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: KIDLINGTON, OXFORD : PERGAMON-ELSEVIER SCIENCE
Pages: - Volume / Issue: 37 (16) Sequence Number: - Start / End Page: 2753 - 2756 Identifier: ISSN: 0040-4039