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キーワード:
SOLID-PHASE SYNTHESIS; CHEMICAL-ENZYMATIC SYNTHESIS; TYROSINE KINASE INHIBITORS; THREONINE BUILDING-BLOCKS; PROTECTING GROUP; GLYCOPEPTIDE SYNTHESIS; LAVENDUSTIN-A; PROTEIN-PHOSPHORYLATION; CELLULAR-REGULATION
Chemistry; bio-organic chemistry; enzyme inhibition; organic synthesis; peptide conjugates; signal transduction;
要旨:
Today, many biological phenomena are being both investigated and understood in molecular detail, and organic chemistry is increasingly being directed towards biological phenomena. Thus, the field of "bioorganic chemistry", which encompasses both biological and chemical research, has developed at the border between these two disciplines. The interplay of organic chemistry and biology will be illustrated in this review, using biological signal transduction as an example.
