Characterization of Irreversible Kinase Inhibitors by Directly Detecting 
Covalent Bond Formation: A Tool for Dissecting Kinase Drug Resistance

Klüter, Sabine; Simard, Jeffrey R.; Rode, Haridas B.; Grütter, Christian; Pawar, Vijaykumar; Raaijmakers, Hans C A.; Barf, Tjeerd A.; Rabiller, Matthias; van Otterlo, Willem A. L.; Rauh, Daniel

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Characterization of Irreversible Kinase Inhibitors by Directly Detecting Covalent Bond Formation: A Tool for Dissecting Kinase Drug Resistance

Klüter, S., Simard, J. R., Rode, H. B., Grütter, C., Pawar, V., Raaijmakers, H. C. A., et al. (2010). Characterization of Irreversible Kinase Inhibitors by Directly Detecting Covalent Bond Formation: A Tool for Dissecting Kinase Drug Resistance. ChemBioChem, 11(18): 1, pp. 2557-2566. Retrieved from http://dx.doi.org/10.1002/cbic.201000352.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0014-011D-5 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0014-011E-3

Genre: Journal Article

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Creators:
Klüter, Sabine¹, Author
Simard, Jeffrey R.¹, Author
Rode, Haridas B.¹, Author
Grütter, Christian¹, Author
Pawar, Vijaykumar¹, Author
Raaijmakers, Hans C A., Author
Barf, Tjeerd A., Author
Rabiller, Matthias¹, Author
van Otterlo, Willem A. L., Author
Rauh, Daniel², Author

Affiliations:
1Max Planck Institute of Molecular Physiology, Max Planck Society, ou_1753286
2Chemical Genomics Center of the MPS, Max Planck Institute of Molecular Physiology, Max Planck Society, ou_1753292

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Free keywords: cancer; drug resistant kinases; EGFR; fluorescence spectroscopy; irreversible inhibitors

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Language(s): eng - English

Dates: Date issued: 2010-12-10

Publication Status: Issued

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Rev. Type: Peer

Identifiers: eDoc: 525509
URI: http://dx.doi.org/10.1002/cbic.201000352

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Title: ChemBioChem

Source Genre: Journal

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Pages: - Volume / Issue: 11 (18) Sequence Number: 1 Start / End Page: 2557 - 2566 Identifier: -