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  The development of a whole-cell based medium throughput screening system for the discovery of human aldosterone synthase (CYP11B2) inhibitors: Old drugs disclose new applications for the therapy of congestive heart failure, myocardial fibrosis and hypertension

Hakki, T., Hübel, K., Waldmann, H., & Bernhardt, R. (2011). The development of a whole-cell based medium throughput screening system for the discovery of human aldosterone synthase (CYP11B2) inhibitors: Old drugs disclose new applications for the therapy of congestive heart failure, myocardial fibrosis and hypertension. Journal of Steroid Biochemistry and Molecular Biology, 125: 1, pp. 120-128. Retrieved from http://dx.doi.org/10.1016/j.jsbmb.2010.12.011.

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 Creators:
Hakki, Tarek, Author
Hübel, Katja1, Author
Waldmann, Herbert2, Author           
Bernhardt, Rita, Author
Affiliations:
1Max Planck Institute of Molecular Physiology, Max Planck Society, ou_1753286              
2Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society, ou_1753290              

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Free keywords: CYP11Bs; Hyperaldosteronism; Hypertension; Heart failure; Myocardial fibrosis; Screening system; Drug discovery; Drug recycling
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Language(s): eng - English
 Dates: 2011
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 570056
URI: http://dx.doi.org/10.1016/j.jsbmb.2010.12.011
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Title: Journal of Steroid Biochemistry and Molecular Biology
Source Genre: Journal
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Publ. Info: -
Pages: - Volume / Issue: 125 Sequence Number: 1 Start / End Page: 120 - 128 Identifier: -