Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS 
signalling

Zimmermann, Gunther; Papke, Björn; Ismail, Shehab; Vartak, Nachiket; Chandra, Anchal; Hoffmann, Maike; Hahn, Stephan A.; Triola, Gemma; Wittinghofer, Alfred; Bastiaens, Philippe I. H.; Waldmann, Herbert

doi:10.1038/nature12205

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Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling

Zimmermann, G., Papke, B., Ismail, S., Vartak, N., Chandra, A., Hoffmann, M., et al. (2013). Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling. Nature, 497(7451): 1, pp. 638-642. doi:10.1038/nature12205.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0013-FD8E-2 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0014-F443-3

Genre: Journal Article

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Creators:
Zimmermann, Gunther¹, Author
Papke, Björn², Author
Ismail, Shehab³, Author
Vartak, Nachiket², Author
Chandra, Anchal², Author
Hoffmann, Maike⁴, Author
Hahn, Stephan A.⁴, Author
Triola, Gemma¹, Author
Wittinghofer, Alfred³, Author
Bastiaens, Philippe I. H.², Author
Waldmann, Herbert¹, Author

Affiliations:
1Abt. IV: Chemische Biologie, Max Planck Institute of Molecular Physiology, Max Planck Society, ou_1753290
2Abt. II: Systemische Zellbiologie, Max Planck Institute of Molecular Physiology, Max Planck Society, ou_1753288
3Sonstige Wissenschaftliche Organisationseinheiten, Max Planck Institute of Molecular Physiology, Max Planck Society, ou_1753294
4External Organizations, ou_persistent22

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Language(s): eng - English

Dates: Date issued: 2013-05-30

Publication Status: Issued

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Rev. Type: Peer

Identifiers: eDoc: 656223
DOI: 10.1038/nature12205

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Title: Nature

Source Genre: Journal

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Pages: - Volume / Issue: 497 (7451) Sequence Number: 1 Start / End Page: 638 - 642 Identifier: -