hide
Free keywords:
-
Abstract:
In this paper, CBF-based functional imaging is reported at sub-millimeter resolution (0.9 mm) in humans for the first time. High sensitivity was made possible by signal-to-noise gains at the high magnetic field of 7 Tesla and by using a novel RF combination coil design. In addition, 0.9-mm in-plane resolution with gradient-echo echo-planar imaging was achieved in a single-shot by reducing the field-of-view. Functional CBF data were compared with functional BOLD data to reveal that the CBF response was more localized and that, for CBF, large contrast-to-noise gains were obtained at high spatial resolution.