Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

 
 
DownloadE-Mail
  A multivariate approach for processing magnetization effects in triggered event-related functional magnetic resonance imaging time series

Esposito, F., di Salle F, Hennel F, Santopaolo O, Herdener M, Scheffler, K., Goebel, R., & Seifritz, E. (2006). A multivariate approach for processing magnetization effects in triggered event-related functional magnetic resonance imaging time series. NeuroImage, 30(1), 136-143. doi:10.1016/j.neuroimage.2005.09.012.

Item is

Externe Referenzen

einblenden:

Urheber

einblenden:
ausblenden:
 Urheber:
Esposito, F, Autor
di Salle F, Hennel F, Santopaolo O, Herdener M, Scheffler, K1, Autor           
Goebel, R, Autor
Seifritz, E, Autor
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              

Inhalt

einblenden:
ausblenden:
Schlagwörter: -
 Zusammenfassung: Triggered event-related functional magnetic resonance imaging requires sparse intervals of temporally resolved functional data acquisitions, whose initiation corresponds to the occurrence of an event, typically an epileptic spike in the electroencephalographic trace. However, conventional fMRI time series are greatly affected by non-steady-state magnetization effects, which obscure initial blood oxygen level-dependent (BOLD) signals. Here, conventional echo-planar imaging and a post-processing solution based on principal component analysis were employed to remove the dominant eigenimages of the time series, to filter out the global signal changes induced by magnetization decay and to recover BOLD signals starting with the first functional volume. This approach was compared with a physical solution using radiofrequency preparation, which nullifies magnetization effects. As an application of the method, the detectability of the initial transient BOLD response in the auditory cortex, which is elicited by the onset of acoustic scanner noise, was used to demonstrate that post-processing-based removal of magnetization effects allows to detect brain activity patterns identical with those obtained using the radiofrequency preparation. Using the auditory responses as an ideal experimental model of triggered brain activity, our results suggest that reducing the initial magnetization effects by removing a few principal components from fMRI data may be potentially useful in the analysis of triggered event-related echo-planar time series. The implications of this study are discussed with special caution to remaining technical limitations and the additional neurophysiological issues of the triggered acquisition.

Details

einblenden:
ausblenden:
Sprache(n):
 Datum: 2006-03
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: -
 Identifikatoren: URI: http://www.sciencedirect.com/science/article/pii/S1053811905006968
DOI: 10.1016/j.neuroimage.2005.09.012
BibTex Citekey: EspositoDHSHSGS2006
 Art des Abschluß: -

Veranstaltung

einblenden:

Entscheidung

einblenden:

Projektinformation

einblenden:

Quelle 1

einblenden:
ausblenden:
Titel: NeuroImage
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: 30 (1) Artikelnummer: - Start- / Endseite: 136 - 143 Identifikator: -