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  Insights into the dynamics of hemodynamic response to millisecond stimulus duration: A fMRI and VEP study

Yesilyurt, B., Whittingstall, K., Ugurbil, K., & Uludag, K. (2007). Insights into the dynamics of hemodynamic response to millisecond stimulus duration: A fMRI and VEP study. Talk presented at 2007 Joint Annual Meeting ISMRM-ESMRMB. Berlin, Germany.

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Yesilyurt, B1, Author           
Whittingstall, K2, Author           
Ugurbil, K, Author
Uludag, K1, Author           
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              

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 Abstract: In a previous study, we have shown that in human subjects it is possible to detect blood oxygenation level dependent (BOLD) signal changes evoked by a visual stimulus presented only for 5 ms. Moreover, we observed that at this ultrashort stimulus duration a) the response is highly non-linear compared to 50ms, 250ms and 1s stimulus b) the extrapolated intercept at 0ms stimulus duration was not zero. That is, below specific stimulus duration the hemodynamic response remains constant. In this study, we have expanded our previous investigation on the temporal behaviour of the BOLD response by zooming into the time scale of stimulus durations as short as 0.1 to 5ms, in order to evaluate if there is indeed a minimum hemodynamic response. Moreover, in order to gain insights about the dynamics of neural response at ultrashort stimulus durations, we also performed VEP recordings to complement the fMRI data.

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 Dates: 2007-05
 Publication Status: Issued
 Pages: -
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 Rev. Type: -
 Identifiers: URI: http://www.ismrm.org/07/
BibTex Citekey: 5938
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Title: 2007 Joint Annual Meeting ISMRM-ESMRMB
Place of Event: Berlin, Germany
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