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  Dynamics of Lactate Concentration and BOLD Effect Upon Repeated Identical Visual Stimuli

Mangia, S., Tkac I, Logothetis, N., Van de Moortele P-F, Gruetter, R., & Ugurbil, K. (2007). Dynamics of Lactate Concentration and BOLD Effect Upon Repeated Identical Visual Stimuli. Poster presented at 2007 Joint Annual Meeting ISMRM-ESMRMB, Berlin, Germany.

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 Urheber:
Mangia, S, Autor
Tkac I, Logothetis, NK1, Autor           
Van de Moortele P-F, Gruetter, R, Autor
Ugurbil, K, Autor
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              

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 Zusammenfassung: In vivo 1H NM spectroscopy at 7 T was utilized to measure the changes of lactate concentration upon repeated identical visual stimuli, each lasting 2 min. The amplitude of these changes was attenuated from the initial value of 0.2 μmol/g and gradually disappeared in the noise. In sharp contrast, the Blood Oxygen Level Dependent (BOLD) effect was persistent during the whole paradigm. This finding may suggest a differential adaptation of cortical output that is not reflected at the level of the global excitation-inhibition activity of the cortical canonical circuits.

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 Datum: 2007-05
 Publikationsstatus: Erschienen
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 Identifikatoren: URI: http://www.ismrm.org/07/
BibTex Citekey: MangiaTLVGU2077
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Titel: 2007 Joint Annual Meeting ISMRM-ESMRMB
Veranstaltungsort: Berlin, Germany
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