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Zusammenfassung:
Complementary non-invasive imaging methods on human subjects such as EEG and fMRI can provide new insights into the functioning of the brain and into neurovascular coupling. Particularly, short stimulus durations rather than commonly used standard durations in fMRI experiments are suitable to study the relationship between electrophysiological and vascular measures because of reduction of non-linearities of the hemodynamic response [1]. In this study, using very short stimulus durations (0.1 ms to 5 ms) and measurements with fMRI and EEG we have found that both N75 of the visual evoked potentials and BOLD signal increase and P100 decrease with stimulus duration. In addition, the BOLD signal poststimulus undershoot also tends to deviate more with stimulus duration. These results allow to shed light on whether and which ERP components correlate well with the BOLD signal.
