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  BOLD sensitivity to cortical activation induced by microstimulation: comparison to visual stimulation

Sultan, F., Augath, M., & Logothetis, N. (2007). BOLD sensitivity to cortical activation induced by microstimulation: comparison to visual stimulation. Magnetic Resonance Imaging, 25(6), 754-759. doi:10.1016/j.mri.2007.03.014.

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Sultan, F, Autor
Augath, M1, Autor           
Logothetis, NK1, Autor           
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              

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 Zusammenfassung: Electrical microstimulation via intracortical electrodes is a widely used method for deducing functions of the brain. In this study, we compared the spatial extent and amplitude of BOLD responses evoked by intracortical electrical stimulation in primary visual cortex with BOLD activations evoked by visual stimulation. The experiments were performed in anesthetized rhesus monkeys. Visual stimulation yielded activities larger than predicted from the well-established visual magnification factor. However, electrical microstimulation yielded an even greater spread of the BOLD response. Our results confirm that the effects of electrical microstimulation extend beyond the brain region expected to be excited by direct current spread.

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 Datum: 2007-07
 Publikationsstatus: Erschienen
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Titel: Magnetic Resonance Imaging
Genre der Quelle: Zeitschrift
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Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: 25 (6) Artikelnummer: - Start- / Endseite: 754 - 759 Identifikator: -