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Abstract:
Chloride (Cl-) is the most abundant anion in the mammal organism playing an important role in many cellular processes. For instance, plasma
membrane Cl- currents are important for the regulation of excitability in nerve and muscle. Moreover, Cl- ions play a crucial role in controlling the
ionic composition of the cytoplasm and the volume of cells [1]. In order to investigate the feasibility of combined in vivo 35Cl, 23Na and 1H MRI we
developed a rf coil setup to measure 35Cl, 23Na and 1H signals in one scanning session without moving the subject or changing the setup.
