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Abstract:
1H non-water-suppressed MR spectroscopy with the metabolite cycling technique is introduced for measurements in the spinal cord. The high SNR of the water peak allows frequency alignment of FIDs before signal averaging to improve the spectral quality (line shape and SNR) of the metabolite peaks. A study on 3 volunteers demonstrates the feasibility of the method and results in a higher SNR for metabolite cycled spectra as compared with VAPOR water suppressed acquisitions: (mean ± SD) 6.3 ± 0.6, and 4.7 ± 0.6, respectively.